AirDB

AirDB: Angiosperm Immune Receptor Database

AirDB is a user-friendly web application that offers a comprehensive resource of immune receptor and signaling pathway genes across 808 angiosperm genomes, covering basal ANA grade, Chloranthales, Magnoliids, monocots, Ceratophyllales, and dicots. Meanwhile, AirDB integrates convenient online bioinformatical analysis tools, aimed at exploration of immune receptor genes from any newly sequenced genomes or datasets of interest. AirDB also serves as an updated version of the angiosperm NLR atlas ( ANNA ).

Genomes from

808 species

Identifacation of

237 775 NLRs

Identifacation of

379 028 IR-RLKs

Identifacation of

63 440 IR-RLPs

If you use the AirDB, please cite:

[1] Sai-Xi Li, Yang Liu, Yan-Mei Zhang, Jian-Qun Chen, Zhu-Qing Shao. Convergent reduction of immune receptor repertoires during plant adaptation to diverse special lifestyles and habitats. Nat Plants. 2025. doi: 10.1038/s41477-024-01901-x.

[2] Yang Liu, Zhen Zeng, Yan-Mei Zhang, Qian Li, Xing-Mei Jiang, Zhen Jiang, Ji-Hong Tang, Dijun Chen, Qiang Wang, Jian-Qun Chen, Zhu-Qing Shao. An angiosperm NLR Atlas reveals that NLR gene reduction is associated with ecological specialization and signal transduction component deletion. Mol Plant. 2021;14(12):2015-2031. doi: 10.1016/j.molp.2021.08.001.

Contact: If you have any questions about AirDB, please do not hesitate to contact Zhu-Qing Shao or Jian-Qun Chen: zhuqingshao@nju.edu.cn (Z.Q.S.) or chenjq@nju.edu.cn (J.Q.C.)

Gene number comparison

NLR
IR-RLK
IR-RLP

CNL gene number

TNL gene number

RNL gene number

Duf26-RLK gene number

G-lectin-RLK gene number

L-lectin-RLK gene number

LRR-RLK gene number

LRR-RLK XII gene number

LysM-RLK gene number

Malectin-RLK gene number

WAK-RLK gene number

LRR-RLP gene number

LRR-RLP ID+4LRR gene number

LysM-RLP gene number

Clade

Order

Family

Genus

Species

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Taxon and Genome Information

Immune Receptor Gene Number

Type of immune receptor

Subfamily of immune receptor

Subgroup of immune receptor

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Type for identification

Candidate Immune Receptor Gene List

Gene List

Overview of Identification Result

Enter query protein sequences in fasta format:

Sequences Producing Significant Alignments Gene List

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808 angiosperms taxa and genome information

NLR protein sequences

IR-RLK protein sequences

IR-RLP protein sequences

EDS1 family protein sequences

cTIR protein sequences

TNP protein sequences

MLKL protein sequences

AirDB: Angiosperm Immune Receptor Database

Blastp Parameters